Ghostbusters: Sanctum of Slime is the smaller-scale Ghostbusters follow-up that hands the proton packs to a rookie squad instead of the classic four. It plays like a top-down co-op action game, sends the team across hotels, hospitals, sewers, graveyards, and city streets, and keeps its story tied to Janosz Poha, the Relic of Nilhe, and Dumazu the Destroyer.
This section is the new front desk for the game. If you want the broad overview first, start here. If you already know what you need, jump straight to the cast, character, level, or ghost pages below.
Start here
- Cast list – the story roster, split into the rookie team, Firehouse support, and the main villains.
- Character list – quick bios for the rookies, the classic team in support, Geoff, Janosz, and Ismael.
- Level list – all 12 levels, with the location, key threats, and boss-guide links where the campaign turns into a major fight.
- Ghost list – the enemy roster, from Master Chef LaBlog and the Subway Smasher to Tomb Effigy and Dumazu.
- Credits – key development, art, audio, and publishing credits, plus a note on the lack of a credited voice cast.
- Weapons and equipment – the plain-English breakdown of the red, yellow, and blue weapon system.
- Stay Puft collectibles – a near-printable checklist with the exact level-area placements.
- Boss guide – the hub for every major fight, with idiot-proof color and attack explanations.
- Walkthrough hub – the mission-by-mission campaign guide with area-by-area notes.
Game at a glance
- Developer: Behaviour Santiago
- Publisher: Atari
- Platforms: Windows, PlayStation 3, Xbox 360
- Release window: March 2011
- Play style: Single-player or four-player co-op
- Camera and combat style: Top-down action with color-swapping proton attacks and trap-focused boss fights
How long to beat Ghostbusters: Sanctum of Slime
HowLongToBeat currently lists these rough player-reported times for Ghostbusters: Sanctum of Slime:
- Main Story: about 3h 34m
- Main + Extra: about 4h 5m
- Completionist: about 5h 53m
Source: HowLongToBeat – Ghostbusters: Sanctum of Slime. These numbers can shift over time as more players log their runs.
Story setup
The plot spins out of an old cult tied to Dumazu the Destroyer and a broken artifact called the Relic of Nilhe. Janosz Poha gets pulled back into the mess, Ismael hides behind the alias Dr. Michael Tesmon, and the original Ghostbusters are spread thin enough that they finally turn to a younger team for help.
That rookie squad is Alan Crendall, Samuel Hazer, Bridget Gibbons, and Gabriel Sitter. They do the field work while Peter, Ray, Egon, Winston, Janine, and Geoff support the operation from the Firehouse and the road.
What makes this game different
- The original team is in the story, but the playable team is a new rookie lineup.
- The campaign mixes standard on-foot stages with two vehicle-heavy street missions in the Ecto-4WD.
- Enemy color auras matter. Swapping to the right stream type is part of the rhythm, not an optional extra.
- The cutscenes lean into comic-book framing, which gives the game a slightly different feel than Ghostbusters: The Video Game.
- The campaign builds toward a straight-up boss rush before the final Ismael and Dumazu showdown.